All Issue

2015 Vol.47, Issue 2 Preview Page
Permeability Control of Cellulose Hydrogel Membrane Using Alginate

알지네이트를 이용한 셀룰로오스 하이드로겔의 투과 특성 제어

Eunsue Jeong
,
Sungchul Shin
,
Minsung Park
,
Jinho Hyun12†
정은수
,
신성철
,
박민성
,
현진호 12†
Department of Biosystems and Biomaterials Science and Engineering, College of Agriculture and Life Sciences, Seoul National University, 151-921, Seoul
1Center for Food and Bioconvergence, Seoul National University, Seoul 151-921
2Research Institute of Agriculture and Life Sciences, Seoul 151-921
서울대학교 농업생명과학대학 바이오시스템 · 소재학부
1서울대학교 식품바이오융합연구소
2서울대학교 농업생명과학연구원
†jhyun@snu.ac.kr
30 April 2015. pp. 17-23
PDF XML Citation
Abstract

Natural cellulose hydrogel membrane cannot be directly used for cell encapsulation because it has many large pores on the surface that immune biomolecules are able to penetrate into easily. For the reason, alginate was used for the control of pore size of the cellulose hydrogel membrane. The surface morphology of cellulose/alginate nanocomposite confirmed the successful control of the porosity of the membrane. The permeability of the cellulose/alginate nanocomposite was decreased but mechanical properties were increased compared with the bacterial cellulose membrane. The cellulose/alginate nanocomposite could be used for the functional membrane as a promising biomedical material in the future.

Keywords
Cellulose hydrogel
Alginate
Nanocomposite
Cell encapsulation
Permeability
Porosity control
Mechanical property
References

Literature Cited

1
C.C. Lin and K. S. Anseth, PNAS, Cell-cel communication mimicry with poly(ethylene glycol) hydrogels for enhancing β-cell function, 108(16); 6380-6385 (2011)10.1073/pnas.1014026108
2
C. H. Goh, P. W. S. Heng and L. W. Chan, Carbohydrate Polymers, Alginate as a useful naturalpolymer for microencapsulation and therapeutic applications, 88; 1-12 (2012)10.1016/j.carbpol.2011.11.012
3
K. K. Hall, K. M. Gattas-Asfura and C. L. Stabler, Acta biomaterialia, Microencapsulation of islets within alginate/poly (ethylene glycol) gels cross-linked via Staudinger ligation, 7(2); 614-624 (2011)10.1016/j.actbio.2010.07.016
4
W. H. Tan and S. Takeuchi, Advanced Materials, Monodisperse alginate hydrogel microbeads for cell encapsulation, 19(18); 2696-2701 (2007)10.1002/adma.200700433
5
M. A. Jafar Mazumder, N. A. Burke, F. Shen, M. A. Potter and H. D. Stover, Biomacromolecules, Core-cross-linked alginate microencapsules for cell encapsulation, 10(6); 1365-1373 (2009)10.1021/bm801330j
6
W. Zhang, S. Zhao, W. Rao, J. Snyder, J. K. Choi, J. Wang, I. A. Khan, N. B. Saleh, P. J. Mohler, J. Yu, T. J. Hund, C. Tang and X. He, Journal of materials chemistry B, A novel core-shell microcapsule for encapsulation and 3D culture for embryonic stem cells, 7; 1002-1009 (2013)10.1039/C2TB00058J
7
A. M. Sokolnicki, R. J. Fisher, T. P. Harrah and D. L. Kaplan, Journal of membrane science, Permeability of bacterial cellulose membranes, 272(1-2); 15-27 (2006)10.1016/j.memsci.2005.06.065
8
Y. Li, S. Qing, J. Zhou and G. Yang, Carbohydrate polymers, Evaluation of bacterial cellulose/hyaluronan nanocomposite biomaterials, 103; 496-501 (2014)10.1016/j.carbpol.2013.12.059
9
M. Zaborowaska, A. Bodin, H. Backdahl, J. Popp, A. Goldstein and P. Gatenholm, Acta biomaterialia, Microporous bacterial cellulose as a potential scaffold for bone regeneration, 6(7); 2540-2547 (2010)10.1016/j.actbio.2010.01.004
10
C. Yang, C. Gao, Y. Wan, T. Tang, S. Zhang and K. Dai, Journal of porous materials, Preparation and characteriazation of three-dimensional nanostructured macroporous bacterial cellulose/agarose scaffold for tissue engineering, 18(5); 545-552 (2011)10.1007/s10934-010-9407-z
11
C. Gao, Y. Wan, C. Yang, K. Dai, T. Tang, H. Luo and J. Wang, Journal of porous materials, Preparation and characterization of bacterial cellulose sponge with hierarchical pore structure as tissue engineering scaffold, 18(2); 139-145 (2011)10.1007/s10934-010-9364-6
12
A. Kang, J. Park, G. S. Jeong and S. H. Lee, Biomaterials, Cell encapsulation via microtechnologies, 35(9); 2651-2663 (2014)10.1016/j.biomaterials.2013.12.073
Information
  • Publisher :Korea Technical Association of The Pulp and Paper Industry
  • Publisher(Ko) :한국펄프종이공학회
  • Journal Title :Journal of Korea TAPPI
  • Journal Title(Ko) :펄프종이기술
  • Volume : 47
  • No :2
  • Pages :17-23
  • Received Date : 2015-03-03
  • Revised Date : 2015-04-15
  • Accepted Date : 2015-04-19
  • DOI :https://doi.org/10.7584/ktappi.2015.47.2.017
Journal Informaiton Journal of Korea TAPPI Journal of Korea TAPPI
Online Submission
  • scopus
  • NRF
  • KOFST
  • crossref crossmark
  • crossref cited-by
  • crosscheck
  • orcid
Journal Informaiton Journal Informaiton - close