Review
Khalil, H. A., Davoudpour, Y., Islam, M. N., Mustapha, A., Sudesh, K., Dungani, R., and Jawaid, M., Production and modification of nanofibrillated cellulose using various mechanical processes: A review, Carbohydr. Polym. 99:649-665 (2014).
10.1016/j.carbpol.2013.08.06924274556Navarra, M. A., Dal Bosco, C., Serra Moreno, J., Vitucci, F. M., Paolone, A., and Panero, S., Synthesis and characterization of cellulose-based hydrogels to be used as gel electrolytes, Membranes 5:810-823 (2015).
10.3390/membranes504081026633528PMC4704013Moon, R. J., Martini, A., Nairn, J., Simonsen, J., and Youngblood, J., Cellulose nanomaterials review: Structure, properties and nanocomposites, Chem. Soc. Rev. 40:3941-3994 (2011).
10.1039/c0cs00108b21566801Erfan, H. S., Hengameh, O., Jianfeng, H., Lester, J., Geonzon, C., Rommel, G., Bacabac, Jenneke Klein-Nulend, Seddiqi, H., Oliaei, E., Jin, J., Klein-Nulend, J., Honarkar, H., and Geonzon, L. C., Bacabac, R. G., Cellulose and its derivatives: Towards biomedical applications, Cellulose 28:1893-1931 (2021).
10.1007/s10570-020-03674-wLee, T., Oh, Y., Gwon, J., Hwang, K., Park, J., and Seo, J. Influence of wood pulp properties on the efficiency of carboxymethylation, J. of Korea TAPPI 54:85-93 (2022).
10.7584/JKTAPPI.2022.08.54.4.85Joshi, G., Naithani, S., Varshney, V. K., Bisht, S. S., Rana, V., and Gupta, P. K., Synthesis and characterization of carboxymethyl cellulose from office waste paper: A greener approach towards waste management, Waste Manage. 38:33-40 (2015).
10.1016/j.wasman.2014.11.01525543195Singh, R. K. and Singh, A. K., Optimization of reaction conditions for preparing carboxymethyl cellulose from corn cobic agricultural waste, Waste Biomass Valorization 4:129-137 (2013).
10.1007/s12649-012-9123-9Mondal, M. I. H., Yeasmin, M. S., and Rahman, M. S., Preparation of food grade carboxymethyl cellulose from corn husk agrowaste, Int. J. Biol. Macromol. 79:144-150 (2015).
10.1016/j.ijbiomac.2015.04.06125936282Adinugraha, M. P., Marseno, D. W., and Haryadi, Synthesis and characterization of sodium carboxymethylcellulose from cavendish banana pseudo stem (Musa cavendishii LAMBERT), Carbohydr. Polym. 62:164-169 (2005).
10.1016/j.carbpol.2005.07.019Mondal, M. I. H., Yeasmin, M. S., Rahman, M. S., and Sayeed, M. A., Synthesis and characterization of high-purity food grade carboxymethyl celluloses from different parts of maize waste, In Cellulose and Cellulose Derivatives: Synthesis, Modification and Applications, Mondal, M. I. H. (ed.), Nova Science Publisher, New York, USA, pp. 227-241 (2015).
Yaşar, F., Toğrul, H., and Arslan, N., Flow properties of cellulose and carboxymethyl cellulose from orange peel, J. Food Eng. 81:187-199 (2007).
10.1016/j.jfoodeng.2006.10.022Dai, H. and Huang, H., Enhanced swelling and responsive properties of pineapple peel carboxymethyl cellulose-g-poly(acrylic acid-co-acrylamide) superabsorbent hydrogel by the introduction of carclazyte, J. Agric. Food Chem. 65:565-574 (2017).
10.1021/acs.jafc.6b0489928049294Nascimento, D. M., Nunes, Y. L., Figueirêdo, M. C. B., De Azeredo, H. M. C., Aouada, F. A., Feitosa, J. P. A., Rosa, M. F., and Dufresne, A., Nanocellulose nanocomposite hydrogels: Technological and environmental issues, Green Chem. 20:2428-2448 (2018).
10.1039/C8GC00205CPoodakdee, N. and Thammawichai, W., The effects of the crystallinity index of cellulose on the flexural proeprties of hydrid-cellulose epoxy compoistes, J. Met., Mater. Miner. 34(3):1902 (2024).
10.55713/jmmm.v34i3.1902Yang, F., He, W., Li, H., Zhang, X., and Feng, Y., Role of acid treatment combined with the use of urea in forming cellulose hydrogel, Carbohydr. Polym. 223:115059 (2019).
10.1016/j.carbpol.2019.11505931426985Baek, S. and Park, S., Highly-porous uniformly-sized amidoxime-functionalized cellulose beads prepared by microfluidics with N-methylmorpholine N-oxide, Cellulose 28:5401-5419 (2021).
10.1007/s10570-021-03872-0Zhu, M., Gong, D., Ji, Z., Yang, J., Wang, M., Wang, Z., Tao, S., Wang, X., and Xu, M., Cellulose-reinforced poly(Ionic Liquids) composite hydrogel for infected wounds therapy and real-time reliable bioelectronic, Chem. Eng. J. 476:146816 (2023).
10.1016/j.cej.2023.146816Wang, H., Li, J., Yu, X., Yan, G., Tang, X., Sun, Y., Zeng, X., and Lin, L., Cellulose nanocrystalline hydrogel based on a choline chloride deep eutectic solvent as wearable strain sensor for human motion, Carbohydr. Polym. 255:117443 (2021).
10.1016/j.carbpol.2020.11744333436232Wang, H., Li, J., Yu, X., Zhao, X., Zeng, X., Xu, F., Tang, X., Sun, Y., and Lu, L., Facile fabrication of super-hydrophilic cellulose hydrogel-coated mesh using deep eutectic solvent for efficient gravity-driven oil/water separation, Cellulose 28:949-960 (2021).
10.1007/s10570-020-03578-9Song, M., Pham, T. P. T., and Yun, Y., Ionic liquid-assisted cellulose coating of chitosan hydrogel beads and their application as drug carriers, Sci. Rep. 10:13905 (2020).
10.1038/s41598-020-70900-732807914PMC7431572Xu, M., Huang, Q., Wang, X., and Sun, R., Highly tough cellulose/graphene composite hydrogels prepared from ionic liquids, Ind. Crops Prod. 70:56-63 (2015).
10.1016/j.indcrop.2015.03.004Kundu, R., Mahada, P., Chhirang, B., and Das, B., Cellulose hydrogels: Green and sustainable soft biomaterials, Curr. Res. Green Sustainable Chem. 5:100252 (2022).
10.1016/j.crgsc.2021.100252Peppas, N. A., Bures, P., Leobandung, W., and Ichikawa, H., Hydrogels in pharmaceutical formulations, Eur. J. Pharm. Biopharm. 50:27-46 (2000).
10.1016/S0939-6411(00)00090-410840191Peppas, N. A. and Mikos, A. G., Preparation methods and structure of hydrogels, In Hydrogels in Medicine and Pharmacy, Peppas, N. A. (ed.), CRC Press, Boca Raton, USA, pp. 1-26 (2019).
10.1201/9780429285097-130740237Liu, P., Chen, X., Wang, C., Cui, X., Chen, H., Bai, L., Wang, W., Wei, K., Yang, H., and Yang, L., Humic acid-based anti-freezing and self-healing hydrogel flexible sensors with functional cellulose nanocrystals, Chem. Eng. J. 506:159854 (2025).
10.1016/j.cej.2025.159854Zhang, Y., Shi, Y., and Gong, J., A core/shell structured alginate hydrogel fibers with carboxymethyl cellulose coating for pH responsive color sensor, J. Text. Inst. 1-9 (2025).
10.1080/00405000.2024.2448919Zhang, Y. and Wang, Y., Construction of three-dimensional aerogels from electrospun cellulose fibers as highly efficient and reusable oil absorbents, Sep. Purif. Technol. 353:128604 (2025).
10.1016/j.seppur.2024.128604Boonmahitthisud, A., Nakajima, L., Nguyen, K. D., and Kobayashi, T., Composite effect of silica nanoparticle on the mechanical properties of cellulose-based hydrogels derived from cottonseed hulls, J. Appl. Polym. Sci. 134:1-12 (2017).
10.1002/app.44557Tian, W., Ren, P., Hou, X., Fan, B., Wang, Y., Wu, T., Wang, J., Zhao, Z., and Jin, Y., N-doped holey graphene/porous carbon/cellulose nanofibers electrode and hydrogel electrolyte for low-temperature zinc-ion hybrid supercapacitors, Small 21:e2411657 (2025).
10.1002/smll.20241165739887537Guo, Y., Wang, M., Zhang, Y., Zhao, Z., and Li, J., Advanced hydrogel material for colorectal cancer treatment, Drug Delivery 32:2446552 (2025).
10.1080/10717544.2024.2446552PMC11703513Kloster, M., Marcovich, N. E., and Mosiewicki, M. A., Microcrystalline cellulose modified chitosan aerogels to enhance Congo Red dye adsorption, Colloids Surf., A, Physicochem. Eng. Aspects 707:135823 (2025).
10.1016/j.colsurfa.2024.135823Hu, X., Wang, Y., Guo, Y., Zhou, G., Liu, S., and Li, J., Bismuth sodium titanate-enhanced microfibrillated cellulose/poly(acrylic acid) double-network piezoelectric hydrogel for a self-powered, flexible, and durable strain sensor, ACS Appl. Polym. Mater. 7:1805-1817 (2025).
10.1021/acsapm.4c03601Ye, D., Chang, C., and Zhang, L., High-strength and tough cellulose hydrogels chemically dual cross-linked by using low- and high-molecular-weight cross-linkers, Biomacromolecules 20:1989-1995 (2019).
10.1021/acs.biomac.9b0020430908016Wei, P., Yu, X., Fang, Y., Wang, L., Zhang, H., Zhu, C., and Cai, J., Strong and tough cellulose hydrogels via solution annealing and dual cross-linking, Small 19:2301204 (2023).
10.1002/smll.20230120436967542Dickinson, E., Microgels - An alternative colloidal ingredient for stabilization of food emulsions, Trends Food Sci. Technol. 43:178-188 (2015).
10.1016/j.tifs.2015.02.006Yang, Y., Sha, L., Zhao, H., Guo, Z., Wu, M., and Lu, P., Recent advances in cellulose microgels: Preparations and functionalized applications, Adv. Colloid Interface Sci. 311:102815 (2023).
10.1016/j.cis.2022.10281536427465Wang, H., Yu, X,. Tang, X., Sun, Y., Zeng, X., and Lin, L., A self-healing water-dissolvable and stretchable cellulose-hydrogel for strain sensor, Cellulose 29:1-14 (2022).
10.1007/s10570-021-04321-8Murray, B. S., Microgels at fluid-fluid interfaces for food and drinks, Adv. Colloid Interface Sci. 271:101990 (2019).
10.1016/j.cis.2019.10199031330395Yu, J., Xiao, J., Wang, Y., Zhang, T. C., Li, J., He, G., and Yuan, S., N, P co-doped cellulose-based carbon aerogel: A dual-functional porous material for CO2 capture and supercapacitor, Sep. Purif. Technol. 359:130569 (2024).
10.1016/j.seppur.2024.130569Martínez-Rico, Ó, Villar, L., Sas, O. G., Domínguez, Á., and González, B., Sustainable cotton decolorization via reversible swelling of cellulosic fibers with N-methylmorpholine-N-oxide aqueous solutions, Environ. Technol. Innovation 37:103940 (2025).
10.1016/j.eti.2024.103940Salas, R., Villa, R., Velasco, F., Cirujano, F. G., Nieto, S., Martin, N., Garcia-Verdugo, E., Dupont, J., and Lozano, P., Ionic liquids in polymer technology, Green Chem. 27:1620-1651 (2025).
10.1039/D4GC05445HLi, K., Chen, X., Wang, Y., Sun, B., Yuan, Z., and Liu, Y., Regenerated cellulose microgel: A promising reinforcing agent and gelator for soft matter, ACS Appl. Polym. Mater. 3:4101-4108 (2021).
10.1021/acsapm.1c00588Torres, O., Murray, B., and Sarkar, A., Emulsion microgel particles: Novel encapsulation strategy for lipophilic molecules, Trends Food Sci. Technol. 55:98-108 (2016).
10.1016/j.tifs.2016.07.006Navarro Arrebola, I., Billon, L., and Aguirre, G., Microgels self-assembly at liquid/liquid interface as stabilizers of emulsion: Past, present & future, Adv. Colloid Interface Sci. 287:102333 (2021).
10.1016/j.cis.2020.10233333360120Schmitt, V., Destribats, M., and Backov, R., Colloidal particles as liquid dispersion stabilizer: Pickering emulsions and materials thereof, Comptes Rendus. Physique 15:761-774 (2014).
10.1016/j.crhy.2014.09.010Du, L. and Meng, Z., Engineering surfactant-free pickering double emulsions gels with different structures as low-calorie fat analogues: Tunable oral perception, inhibiting lipid digestion, and potent co-delivery for lycopene and epigallocatechin gallate, Food Chem. 463:141378 (2025).
10.1016/j.foodchem.2024.14137839332359Ramos, G. V. C., Ramírez-López, S., Pinho, S. C. D., Ditchfield, C., and Moraes, I. C. F., Starch-based pickering emulsions for bioactive compound encapsulation: Production, Properties, and Applications, Processes 13:342 (2025).
10.3390/pr13020342Ji, C., Wang, Y., Ma, A. W. K., Liang, Y., and Luo, Y., Physicochemical and rheological characterization of plant-based proteins, pectin, and chitin nanofibers for developing high internal phase Pickering emulsions as potential fat alternatives, Food Chem. 472:142975 (2025).
10.1016/j.foodchem.2025.14297539855142Cai, F., Duan, Z., Yu, D., Song, Z., and Lu, P., Antimicrobial packaging activity enhancement by lemon essential oil pickering emulsion stabilized with nanocellulose microgel particles, Food Packag. Shelf Life 47:101439 (2025).
10.1016/j.fpsl.2025.101439Nie, C., Ye, Q., Chen, J., Zhuo, J., and Xiao, J., Influence of polysaccharide stabilizer and polyglycerol polyricinoleate on the stability of pickering double emulsions via microfluidic technology, Food Hydrocolloids 163:111046 (2025).
10.1016/j.foodhyd.2025.111046Rommel, D., Häßel, B., Pietryszek, P., Mork, M., Jung, O., Emondts, M., Norkin, N., Doolaar, I. C., Kittel, Y., Yazdani, G. A., Omidinia-anarkoli, A., Schweizerhof, S., Kim, K., Mourran, A., Möller, M., Guck, J., and De Laporte, L., Thermally assisted microfluidics to produce chemically equivalent microgels with tunable network morphologies, Angew. Chem., Int. Ed. 64:e202411772 (2025).
10.1002/anie.20241177239453733Zhang, B., Sun, B., Li, X., Yu, Y., Tian, Y., Xu, X., and Jin, Z., Synthesis of pH- and ionic strength-responsive microgels and their interactions with lysozyme, Int. J. Biol. Macromol. 79:392-397 (2015).
10.1016/j.ijbiomac.2015.05.01126001494Lu, P., Zhao, H., Zheng, L., Duan, Y., Wu, M., Yu, X., and Yang, Y., Nanocellulose/Nisin hydrogel microparticles as sustained antimicrobial coatings for paper packaging, ACS Appl. Polym. Mater. 4:2664-2673 (2022).
10.1021/acsapm.2c00001Shen, X., Shamshina, J. L., Berton, P., Gurau, G., and Rogers, R. D., Hydrogels based on cellulose and chitin: Fabrication, properties, and applications, Green Chem. 18:53-75 (2016).
10.1039/C5GC02396CTang, Y., Fang, Z., and Lee, H., Exploring applications and preparation techniques for cellulose hydrogels: A comprehensive review, Gels 10:365 (2024).
10.3390/gels1006036538920912PMC11203356Kabir, S. M. F., Sikdar, P. P., Haque, B., Bhuiyan, M. A. R., and Ali, A., Islam, M. N., Cellulose-based hydrogel materials: Chemistry, properties and their prospective applications, Prog. Biomater. 7:153-174 (2018).
10.1007/s40204-018-0095-030182344PMC6173681Zhang, S., Gatsi, B., Yao, X., Jin, Y., and Amhal, H., Cellulose nanofiber-reinforced antimicrobial and antioxidant multifunctional hydrogel with self-healing, adhesion for enhanced wound healing, Carbohydr. Polym. 352:123189 (2025).
10.1016/j.carbpol.2024.12318939843092Jeong, J., Park, D., Kim, S., Kang, H. W., Lee, B., Kim, H., Kim, Y., Linh, N. V., and Jung, W., Wound healing effect of fucoidan-loaded gelatin/oxidized carboxymethyl cellulose hydrogel, Int. J. Biol. Macromol. 286:138254 (2025).
10.1016/j.ijbiomac.2024.13825439631587Orhan, B., Karadeniz, D., Kalaycıoğlu, Z., Kaygusuz, H., Torlak, E., and Erim, F. B., Foam-based antibacterial hydrogel composed of carboxymethyl cellulose/polyvinyl alcohol/cerium oxide nanoparticles for potential wound dressing, Int. J. Biol. Macromol. 291:138924 (2025).
10.1016/j.ijbiomac.2024.13892439708892Seo, M., Seo, M., Choi, S., Shin, K., Lee, J. B., Yang, D., and Kim, J. W., Cellulose nanofiber-multilayered fruit peel-mimetic gelatin hydrogel microcapsules for micropackaging of bioactive ingredients, Carbohydr. Polym. 229:115559 (2020).
10.1016/j.carbpol.2019.11555931826459Ebrahimi, Y., Peighambardoust, S. J., Peighambardoust, S. H., and Karkaj, S. Z., Development of antibacterial carboxymethyl cellulose-based nanobiocomposite films containing various metallic nanoparticles for food packaging applications, J. Food Sci. 84:2537-2548 (2019).
10.1111/1750-3841.1474431433502Li, C., Zhou, X., Zhu, L., Xu, Z., Tan, P., Wang, H., Chen, G., and Zhou, X., Tough hybrid microgel-reinforced hydrogels dependent on the size and modulus of the microgels, Soft Matter 17:1566-1573 (2021).
10.1039/D0SM01703E33346314Li, M., Guo, L., Mu, Y., Huang, X., Jin, L., Xu, Q., and Wang, Y., Gelatin films reinforced by tannin-nanocellulose microgel with improved mechanical and barrier properties for sustainable active food packaging, Food Hydrocolloids 149:109642 (2024).
10.1016/j.foodhyd.2023.109642Liu, X., Wang, X., Liao, W., Sun, T., Feng, A., Sun, X., Zhao, Y., Yang, W., and Templonuevo, R. M. C., Construction and properties of bacterial cellulose/chitosan microgel films loaded with ε-polylysine and its application on Tilapia preservation, Food Packag. Shelf Life 47:101433 (2025).
10.1016/j.fpsl.2025.101433Cai, F., Duan, Z., Yu, D., Song, Z., and Lu, P., Antimicrobial packaging activity enhancement by lemon essential oil pickering emulsion stabilized with nanocellulose microgel particles, Food Packag. Shelf Life 47:101439 (2025).
10.1016/j.fpsl.2025.101439Huang, K. and Wang, Y., Recent applications of regenerated cellulose films and hydrogels in food packaging, Curr. Opin. Food Sci. 43:7-17 (2022).
10.1016/j.cofs.2021.09.003Al-Hazmi, G. A. A. M., Elsayed, N. H., Alnawmasi, J. S., Alomari, K. B., Alessa, A. H., Alshareef, S. A., and El-Bindary, A. A., Elimination of Ni(II) from wastewater using metal-organic frameworks and activated algae encapsulated in chitosan/carboxymethyl cellulose hydrogel beads: Adsorption isotherm, kinetic, and optimizing via Box-Behnken design optimization, Int. J. Biol. Macromol. 299:140019 (2025).
10.1016/j.ijbiomac.2025.14001939848370Yi, C., Niu, H., Sui, L., Zhu, J., Tian, Y., Niu, C., Chen, Z., Wei, H., and Huang, D., A low-cost bio-based cellulose composite hydrogel with cross-linked structures for efficient capture of heavy metal ions, Sep. Purif. Technol. 358:130213 (2025).
10.1016/j.seppur.2024.130213Wang, X., Luo, S., Luo, J., Liu, L., Hu, L., Li, Z, Jiang, L., and Qin, H., Fluorescent cellulose nanofibrils hydrogels for sensitive detection and efficient adsorption of Cu2+ and Cr6+, Carbohydr. Polym. 347:122748 (2025).
10.1016/j.carbpol.2024.12274839486977Liu, Z., Li, R., Hou, Y., Guo, J., Li, X., Li, K., and Liu, Q., Durable PVA-based hydrogel sponge with cellulose whiskers embedded in the 3D interconnected channels for efficient oil/water separation, Carbohydr. Polym. 352:123251 (2025).
10.1016/j.carbpol.2025.12325139843131Zhao, D., Zhu, Y., Cheng, W., Chem, W., Wu, Y., and Yu, H., Cellulose-based flexible functional materials for emerging intelligent electronics, Adv. Mater. 30:2000619 (2021).
10.1002/adma.20200061932310313Zou, Y., Liao, Z., Zhang, R., Song, S., Yang, Y., Xie, D., Liu, X., Wei, L., Liu, Y., and Song, Y., Cellulose nanofibers/liquid metal hydrogels with high tensile strength, environmental adaptability and electromagnetic shielding for temperature monitoring and strain sensors, Carbohydr. Polym. 348:122788 (2025).
10.1016/j.carbpol.2024.12278839562066Zhang, X., Sun, H., Zhang, J., and Wang, Z., A highly sensitive and stable MXene/bacterial cellulose double network hydrogel flexible strain sensor for human activities monitoring, J. Appl. Polym. Sci. 142:e56468 (2024).
10.1002/app.56468Bai, Y., Bi, S., Wang, W., Ding, N., Lu, Y., and Jiang, M., Biocompatible, stretchable, and compressible cellulose/MXene hydrogel for strain sensor and electromagnetic interference shielding, Soft Mater. 20(4):444-454 (2022).
10.1080/1539445X.2022.2081580Qin, C., Abdalkarim, S. Y. H., Zhou, Y., Yu, H., and He, X., Ultrahigh water-retention cellulose hydrogels as soil amendments for early seed germination under harsh conditions, J. Clean. Prod. 370:133602 (2022).
10.1016/j.jclepro.2022.133602Lee, J. E., Lee, D. Y., Kim, D. H., Oh, Y., Hwang, K., Seo, J., Kim, H., and Lee, T., Influence of hydrogels prepared using carboxymethyl cellulose on water retention in soil, J. of Korea TAPPI 55:83-91 (2023).
10.7584/JKTAPPI.2023.2.55.1.83- Publisher :Korea Technical Association of The Pulp and Paper Industry
- Publisher(Ko) :한국펄프종이공학회
- Journal Title :Journal of Korea TAPPI
- Journal Title(Ko) :펄프종이기술
- Volume : 57
- No :3
- Pages :5-21
- Received Date : 2025-05-27
- Revised Date : 2025-06-13
- Accepted Date : 2025-06-17
- DOI :https://doi.org/10.7584/JKTAPPI.2025.6.57.3.5


Journal of Korea TAPPI






