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2025 Vol.57, Issue 1 Preview Page

Research Article

Optimization of Manufacturing Conditions for Radiation-Crosslinked Hydrogels -Part 2: Investigation of Optimal Conditions Using Response Surface Methodology-

방사선 가교 기반 하이드로겔의 제조 조건 최적화 연구 -제 2보: 반응표면분석법을 이용한 최적 조건 탐색-

Sa Rang Choi1
,
So Yeong Park2
,
Hyeon Ji Im2
,
Jin-hyeong Kim3
,
Jung Myoung Lee4†
최 사랑1
,
박 소영2
,
임 현지2
,
김 진형3
,
이 중명4†
1Agricultural Science and Technology Research Institute, Kyungpook National University
2Major in Wood and Paper Science, Dept. of Wood and Paper Science, School of Forestry, Science and Landscape Architecture, Kyungpook National University
3GEV Co. Ltd., Republic of Korea
4Major in Wood and Paper Science, Dept. of Wood and Paper Science, School of Forestry, Science and Landscape Architecture, Kyungpook National University
1경북대학교 농업과학기술연구소 연구원
2경북대학교 산림과학·조경학부 임산공학전공 학생
3㈜제브 연구원
4경북대학교 산림과학·조경학부 임산공학전공 교수
†Corresponding author: E-Mail: jmylee@knu.ac.kr (Address: Major in Wood and Paper Science, Dept. of Wood and Paper Science, School of Forestry, Science and Landscape Architecture, Kyungpook National University, Daegu, 41566, Republic of Korea)
28 February 2025. pp. 41-49
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Abstract

Electron beam crosslinking is a highly efficient technique that forms crosslinked structures without harmful chemical crosslinkers or catalysts, eliminating the need for additional washing or sterilization. This makes it time- and energy-efficient. In this study, hydrogels were successfully prepared using carboxymethyl cellulose (CMC), a material with excellent hydrophilicity, biodegradability, and non-toxicity, and citric acid (CA), a natural polymer, as a crosslinking agent through electron beam irradiation. To determine optimal mixing conditions, response surface analysis was conducted using the central composite design (CCD) methodology. Results showed that CMC had the most significant impact on the water absorption performance of hydrogels. Excessively low (4.2wt%) or high (9.8wt%) CMC concentrations reduced water absorption. The regression model demonstrated high reliability with an R2 value of 0.91. Based on the response model, optimal conditions for hydrogel preparation were identified as 9.17wt% CMC and 2.92wt% CA. Under these conditions, the predicted water absorption was approximately 79.5 g/g. Validation experiments confirmed these findings, with actual water absorption at 83.8 g/g, showing a +5% error rate. This study provides a predictive model for estimating water absorption based on specific CMC and CA concentrations.

Keywords
Carboxymethyl cellulose
citric acid
hydrogel
electron beam
irradiation crosslinking
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Information
  • Publisher :Korea Technical Association of The Pulp and Paper Industry
  • Publisher(Ko) :한국펄프종이공학회
  • Journal Title :Journal of Korea TAPPI
  • Journal Title(Ko) :펄프종이기술
  • Volume : 57
  • No :1
  • Pages :41-49
  • Received Date : 2025-01-20
  • Revised Date : 2025-02-04
  • Accepted Date : 2025-02-04
  • DOI :https://doi.org/10.7584/JKTAPPI.2025.2.57.1.41
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